Methamphetamine Activates Reward Circuitry in Drug Naı̈ve Human Subjects
نویسندگان
چکیده
Birgit A Völlm*, Ivan E de Araujo, Philip J Cowen, Edmund T Rolls, Morten L Kringelbach, Katharine A Smith, Peter Jezzard, Ronald J Heal and Paul M Matthews Department of Psychiatry, University of Oxford, Warneford Hospital, Oxford, UK; Department of Experimental Psychology, University of Oxford, South Parks Road, Oxford, UK; Centre for Functional Magnetic Resonance Imaging of the Brain, John Radcliffe Hospital, Oxford, UK
منابع مشابه
Current research on methamphetamine: Epidemiology, medical and psychiatric effects, treatment, and harm reduction efforts
Background: Methamphetamine (MA) which is known as “shisheh” in Iran is a drug that widely is used in many parts of the world and it is near to a decade that is available for the most drug users and has a considerable prevalence of use. Due to high abuse prevalence and very new challenging phenomenon, it is very important that researchers and treatment providers become more familiar with differ...
متن کاملMeasurement of Cue-Induced Craving in Human Methamphetamine- Dependent Subjects New Methodological Hopes for Reliable Assessment of Treatment Efficacy
Methamphetamine (MA) is a highly addictive psychostimulant drug with crucial impacts on individuals on various levels. Exposure to methamphetamine-associated cues in laboratory can elicit measureable craving and autonomic reactivity in most individuals with methamphetamine dependence and the cue reactivity can model how craving would result in continued drug seeking behaviors and relapse in rea...
متن کاملBeautiful Faces Have Variable Reward Value fMRI and Behavioral Evidence
The brain circuitry processing rewarding and aversive stimuli is hypothesized to be at the core of motivated behavior. In this study, discrete categories of beautiful faces are shown to have differing reward values and to differentially activate reward circuitry in human subjects. In particular, young heterosexual males rate pictures of beautiful males and females as attractive, but exert effor...
متن کاملMethamphetamine-induced disruption of frontostriatal reward learning signals: relation to psychotic symptoms.
OBJECTIVE Frontostriatal circuitry is critical to learning processes, and its disruption may underlie maladaptive decision making and the generation of psychotic symptoms in schizophrenia. However, there is a paucity of evidence directly examining the role of modulatory neurotransmitters on frontostriatal function in humans. In order to probe the effects of modulation on frontostriatal circuitr...
متن کاملPrenatal Exposure to Maternal Cigarette Smoking and Adolescents’ Reward Processing
Introduction Previous neuroimaging studies demonstrate that drug addiction is characterized by altered reward processing. For example, smokers show an increased reactivity to drug related stimuli in the reward circuitry compared to non-smokers (Due et al., 2002). On the other hand they demonstrate a decreased neural response to non-drug rewards in these areas (Bühler et al., 2010). Animal studi...
متن کامل